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Sex steroids and cardiovascular outcomes in transgender individuals: a systematic review and meta-analysis, J Clin Endocrinol Metab 2017;102(11):3914-3923

The addition of glutamate to folate derivatives traps the molecules in the cell and allows for accumulation in the mitochondria, a process required for the synthesis of glycine
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10.1128/aem.69.10.6128-6132.2003 Appl

Discontinue if concerning effects appear and resume at lower doses if appropriate

Though our focus is on natural therapies, this is a very good time to also add in the antiviral medication Valtrex (Valcyclovir)
