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Neurexins transsynaptic complexes play a central and important role in synaptic plasticity [26, 28], and the role of synaptic plasticity in sustained antidepressant effect has been widely reported [11, 16, 25]

Conversely, the negatively charged properties of GAGs facilitate their introduction to scaffolds or hydrogels containing cationic components via electrostatic interactions

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Prog Neuropsychopharmacol Biol Psychiatry 33(4):625629 United Nations Office on Drugs and Crime (ed) (2011) World Drug Report 2011 Upreti VV, Eddington ND (2008) Fluoxetine pretreatment effects pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA, ECSTASY) in rat