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1-1.5mL pre-lambing Calves 2-3mL from 2 months of age Cows 4-6mL pre-calving
In the research context for separating the effect on central satiety vs peripheral lipolysis

Calcinotto, A., Filipazzi, P., Crioni, M., Iero, M., De Milito, A., Ricupito, A., et al

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However, observational studies suggest that whilst acute toxicity remains exceptionally rare, sustained very high levels of B12particularly from supplements or injectionsmay be associated with certain health concerns, though these are correlations rather than proven causal relationships
