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Using Parkin-null (Park / ) flies, a study showed that folic acid supplementation improved the motor dysfunction and decreases hydrogen peroxide and glutathione redox imbalance [175] where as in fly homozygous for Parkin mutation (c00062), folic acid supplementation improved the mortality, locomotory defect, oxidative stress by alleviating mitochondrial dysfunction associated with Parkin mutation [176]

Although there have been no clinical reports on the use of chili peppers in the treatment of ADHD, its active compounds (CAP, vitamin C, omega-3 PUFAs) have been shown to affect the gut microbiota and its metabolites (see Table 1)

Proceedings of the Royal Society B: Biological Sciences, 284 (1857), 20170356

Bioavailability refers to the amount of a substance that actually enters your circulation and is able to have an active effect

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