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4.1.2 Targeting the inhibition of ferroptosis for the treatment of DN Exploration has been conducted on inhibiting ferroptosis as a therapy for DN

Therefore, these ferroptosis-based oncogenes can be used for the development of new therapeutic drugs

We and others also demonstrated that hemin induces the expression of NRF2 in SCD erythroblasts and animal models and such effect is mitigated by administration of dimethyl fumarate (DMF) 23,24 , an FDA-approved drug for the treatment of multiple sclerosis