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Elevated IGF-1 levels raise concerns about potential proliferative effects on existing malignancies, making growth hormone therapy problematic for individuals with cancer history or elevated cancer risk
mAbs-based approaches In MM, radiolabeled daratumumab, known for its high affinity and specificity for CD38, has been used as a diagnostic tracer for imaging purposes in both preclinical [101, 102] and clinical studies [65, 103]
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