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These metabolites include cytochrome P450 metabolites of arachidonic acids 20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids, cyclooxygenase metabolites prostaglandin E2, prostaglandin I2, and thromboxane A2, and lipoxygenase metabolites leukotrienes, hydroxyeicosatetraenoic acids, and lipoxins

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Recombinant C1q/TNF-related protein 9 (rCTRP9) has the ability to stimulate the AdipoR1/APPL1/AMPK/Nrf2 signaling pathway, which helps decrease neurological impairment in a mouse model of ICH (Zhao et al., 2021)

Moreover, on the scientific front, as the quality of analytical tools increases, we will also need the data to be reproducible and of higher quality

Weinstein EA, Yano T, Li LS, Avarbock D, Avarbock A, Helm D, et al