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Consensus criteria for diagnosis, staging, and treatment response assessment of T-cell prolymphocytic leukemia

doi: 10.3389/fpls.2025.1425880 Received 30 April 2024 Accepted 09 January 2025 Published 20 February 2025 Volume 16 - 2025 Edited by Maria Raffaella Ercolano, University of Naples Federico II, Italy Reviewed by Eva Nouri, Universit de Fribourg, Switzerland Marija Vidovic, University of Belgrade, Serbia Updates Copyright 2025 do Carmo Santos, Silva Santos, Pereira Silva de Novais, dos Santos Lopes, Pirovani and Micheli

Effective therapeutic paradigms appear to converge on modulation of the mitochondrial function, purinergic signaling, and neuroinflammation, often supplemented by nutritional regulators such as vitamin D and retinoids

Glutathione is essential for lymphocyte proliferation (making more immune cells when needed) and for the oxidative burst that immune cells use to kill pathogens