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Efficiency: It allows for a more direct path to the bloodstream, ensuring that more of the active ingredient is available for your body to use

While classical gene mutations are region-limited, epimutations often occur early in cancer development and have a genome-wide impact, boosting on the one hand the expression of cell survival genes or proto-oncogenes and deactivating on the other hand tumor suppressor genes (TSGs), DNA repair mechanisms as well as cell division brakes, thus leading to carcinogenesis (Esteller, 2008

doi: 10.1016/j.nbd.2021.105427 103

Although current evidence primarily stems from preclinical models, a study conducted in rats demonstrated a marked reduction in lipid peroxidation products following allopurinol treatment [106]

10.1016/j.yrtph.2020.104665 [DOI] [PubMed] [Google Scholar] Xue X
