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Animal studies have not shown teratogenic or other embryotoxic effects, but piracetam should still be used during pregnancy only after carefully weighing the expected benefits against the potential risks

The D-glucose 6-phosphate formed is then converted to GDP-D-mannose via four steps reversible process catalyzed by the enzymes phosphogluco-isomerase, mannose 6-phosphate isomerase, phosphomannose mutase and GDP-D-mannose phosphorylase, respectively

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Sasso EM, Muraki K, Eaton-Fitch N, Smith P, Lesslar OL, Deed G, et al

HK supervised all the works
