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Integrated chemical and genetic screens unveil FSP1 mechanisms of ferroptosis regulation
doi:10.1016/j.redox.2013.08.006 Lin SX, Lisi L, Russo CD, Polak PE, Sharp A, Weinberg G, Kalinin S, Feinstein DL (2011) The anti-inflammatory effects of dimethyl fumarate in astrocytes involve glutathione and haem oxygenase-1
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There are two main strategies used to target NRF2 by therapeutic drug treatment: one is NRF2 inhibition, and the other is NRF2 induction

In this section, we will focus on the mammalian biogenesis machinery as a basis to show its involvement in several diseases such as neurodegenerative disorders