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Notably, BBOX expression is nutritionally regulated, being upregulated during fasting conditions, reflecting the adaptive response of endogenous synthesis to dietary availability [72] (Fig

[PMC free article] [PubMed] [Google Scholar] Meyer K., Shea J

Participants self-administered subcutaneous injections of the assigned treatment for 26 weeks

Obese subjects frequently present hyperleptinemia but leptin resistance (Dragano et al., 2017), which contributes to the positive energy balance due to several mechanisms, including the over activation of the ECS signaling in the CNS (Thanos et al., 2008

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