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In addition, investigations indicate that mitochondrial dysfunction in sepsis is a serious factor in organ failure

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Next, the trans -2 double bond is hydrated stereospecifically by an enoyl-CoA hydratase to form an L3hydroxyacyl-CoA, which is in turn oxidized by a hydroxyacyl-CoA dehydrogenase to yield a 3-ketoacyl-CoA with nicotinamide adenine dinucleotide (NAD) reduced to NADH