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Harrison FE

The researchers assessed levels of malondialdehyde (MDA), a marker of oxidative stress, along with enzymatic antioxidants (superoxide dismutase, catalase, glutathione peroxidase) and non-enzymatic antioxidants (reduced glutathione, vitamins A, E, and C) in both the patient group and the healthy controls

The most commonly utilized chemotherapy drug in OS treatment is cisplatin (DDP)

It became the basis for the human clinical trials that followed