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These improvements were ascribed to SFs ability to attenuate LPS-induced pro-inflammatory cytokine production, restore synaptic protein expression, and normalize the BDNF-tropomyosin receptor kinase B (TrkB)-mechanistic target of rapamycin (mTOR) signaling in the hippocampus

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Table 4 Summary of studies investigating the effect of rumen-protected amino acids supplementation on immune function, oxidative and anti-inflammatory status in dairy cattle

This phenomenon has been seen in in vitro culture and in peripheral blood lymphocytes from HIV-infected patients

doi: 10.3389/fpsyt.2025.1584891 48