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The strongest published finding is from the foundational Biochemical Pharmacology study by Neelakantan et al.: in diet-induced obese mice, daily 5-Amino-1MQ administration produced reductions in body weight, white adipose tissue mass, and adipocyte size without any significant change in food intake

The D51 series distinguishes B12 deficiency by its underlying cause, which directly affects coding specificity and reimbursement

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For cohort 1, the ODB database was used to identify patients who were prescribed vitamin B12 injections