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[DOI] [PubMed] [Google Scholar] 58.Hirose T, Sumitomo M, Kudo E, Hasegawa T, Teramae T, Murase M, Higasa Y, Ikata T, Hizawa K

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Interestingly, Pfizer/BioNTech and Moderna specifically use nucleoside-modified mRNA that decrease (rather than increase) the inherent mRNA immunogenicity, underlining the need to properly balance the innate immune activity of mRNA vaccines (see below)

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CMPNs Induce Cell Apoptosis and G2/M Phase Arrest in Gemcitabine-Resistant CCA Cells (KKU-213B GemR ) GemR cells showed significant increases in both early and late apoptotic stages for curcumin and CMPNs treatments compared to the untreated control (Figure 7a,b)