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J Clin Endocrinol Metab 89 : 35433553 Huang Y et al

This pattern indicates that AOD-9604 produces minimal additional symptom burden beyond what would be expected in the absence of treatment

5-Amino-1MQ for Fat Loss and Metabolic Health Murine studies have shown that 5-amino-1MQ can induce significant fat loss and while showing a favorable safety profile
It's not just poor circulation it could be B12-related nerve issues