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( f-g ) H4K12ac or H3K23ac chromatin immunoprecipitation in U2OS-mCherry-LacI-Fok1 cells treated with the IDH1 inhibitor ( f ) or transduced with shRNA targeting TMLHE (shTMLHE) ( g ) alone or supplemented with KG or l-carnitine (l-carn) supplementation (n = 3 technical replicates representative from 2 independent experiments)

[DOI] [PMC free article] [PubMed] [Google Scholar] 262.Kuwasawa-Iwasaki M, Io H, Muto M, Ichikawa S, Wakabayashi K, Kanda R, et al

In subjects with metabolic syndrome, the study revealed that compared to a control group those who received L-carnitine supplements (intravenously) had reduced feelings of hunger and fatigue, as well as improvements in weight loss and other positive effects