glutathione inflammation cancer Tumor-targeted oxidation catalysis with ruthenium nanoreactors against hypoxic osteosarcoma Glutathione-mediated nanomedicines for cancer diagnosis

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systematically reviewed the oxidative stress from the perspectives of oxidants and antioxidants, and noted that oxidants with vastly different half-lives may be observed at the site of generation or be transported to distant target sites where they exert oxidant activities in cell metabolism [63]

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Notably, curcumin, a polyphenolic compound derived from turmeric, has been reported to synergize with azoles and polyenes to amplify ROS generation in Candida albicans , leading to mitochondrial damage, apoptosis, and enhanced antifungal activity (Sharma et al., 2010b

621 Obesity, metabolic syndrome, diet, lifestyle, genetics, and environmental factors contribute to their development