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Enzymatic effectors, such as non-heme, iron-containing proteins, including lipoxygenases (LOXs), can mediate ferroptotic peroxidation (Kagan et al., 2017
10.3389/fphar.2022.991421 82
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Oxidative Med Cell Longev 2015:756294 Vincent A, Brownlee M, Russel J (2002) Oxidative stress and programmed cell death in diabetic neuropathy
Because of this, the functions of MSM may span several cell types, which makes pinpointing its exact direct and indirect effects difficult
