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Micronutrient selenium, which is considered a potent antioxidant, failed to reduce chronic chagasic cardiomyopathy in 66 male and female patients, according to a randomized, placebo-controlled, double-blinded clinical trial [96]

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An intervention trial in 75 adult male smokers found that supplementation with 1,000 mg/day of vitamin C resulted in significantly lower blood lead concentration over a four-week treatment period compared to placebo (219)