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This extrapolation involves two critical decisions: (1) selecting a point of departure (POD), which corresponds to the lowest dose associated with observable adverse effects within the range of data from a study, and (2) selecting the mathematical model used to extrapolate risk from typical human exposures that are well below the POD

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Long-term deficiency can lead to cognitive problems

Especially when we start to train AI models on these type of data

see the next question for why