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buthionine sulfoximine glutathione synthesis inhibitor Markedly Decreased Expression of S-Transferase π Gene in Human Cancer Cell Lines Resistant to Sulfoximine, an of Cellular Glutathione (∗) Synergistic effect of buthionine sulfoximine
Description
Currently, its FDA-approved only for treating methemoglobinemia, although doctors also use it off-label for other conditions

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Importantly, PKD activity was almost completely abolished in PKD3-deficient mice (Fig 4F)

10.3390/toxins9080251 Toxins 45 European Parliament and of the Council, (2002)

Aquat Toxicol 52:189203 Costa J, Ferreira M, Rey-Salgueiro L, Reis-Henriques MA (2011) Comparison of the waterborne and dietary routes of exposure on the effects of benzo(a)pyrene on biotransformation pathways in Nile tilapia ( Oreochromis niloticus )