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Maiorino, R

Within the lipid-rich ascites of ovarian cancer, PUFAs inhibit RhoA-GTPase activity, leading to the downregulation of nuclear YAP1, a critical transcription factor in the Hippo pathway, which dampens antitumor immune responses
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As a key regulator of cellular physiology and pathology, PKM2 is increasingly recognized as a central player in CNS inflammatory diseases (Fig

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