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A novel preventive therapy for paclitaxel-induced cognitive deficits: preclinical evidence from C57BL/6 mice

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Similar to the phenotypes observed when worms are raised on nhr-180 (RNAi), atfs-1(null);nhr-180(cmh19) worms exhibit increased TMRE staining and increased mtDNA content compared to atfs-1(null) worms consistent with a more robust mitochondrial network (Fig