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This thereby accelerates lipid peroxidation and hepatocyte death, ultimately contributing to hepatic inflammation and fibrosis [53]

The cartilage/chondrocyte data supports this

Low temperature reduction of this imide with a reagent obtained from ( R )-binaphthol [( R )-BINAL-H] followed by acetylation furnished the triacetate (3 R ,4 S )- 111 as a single diastereoisomer after chromatographic purification (Scheme 27)

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