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GLUT4 is further induced by insulin-stimulated glucose uptake, revealing that other glucose transporters can contribute to cellular metabolism that supports osteoblast differentiation ( via an mTORC2-AKT axis downstream of Rac Family Small GTPase 1 (RAC1)

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Conclusion Myricetin protects the -cells against HG-induced apoptosis by inhibiting ER stress, possibly through inactivation of CDK5 and consequent upregulation of PDX1 and SERCA2b