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In fact, some evidence suggests that long-term calorie restriction may even increase it a bit
The increased protein binding of hydroxocobalamin sustains circulating vitamin B12 levels for longer than cyanocobalamin

Researchers study it in the context of nicotinamide N methyltransferase activity, methylation related pathways, and cellular metabolism

No pharmacokinetic or pharmacodynamic interaction studies exist for the combination

2022 Jan Amilia Ramadhani, Indwiani Astuti, Maria Goreti Widiastuti, Nunuk Purwanti
