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315 Bimolecular outer-sphere electron-transfer processes are generally slower than inner-sphere electron-transfers but can provide a viable reduction mechanism for platinum(IV) agents in which ligands that are capable of forming a bridge to an electron transfer agent are trans to firmly bound ligands

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In cellular signaling, ROS act as key mediators and regulators, influencing the activity of kinases, phosphatases, transcription factors, and cytoskeletal proteins