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Complex interplay between metabolism and Cd4(+) T-cell activation, differentiation, and function: A novel perspective for atherosclerosis immunotherapy

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Therefore, enhanced glutaminolysis might eventually contribute to the initiation and progression of cancer by stimulating cell growth via the mTORC1 pathway and enhancing aerobic glycolysis while disrupting the proper elimination of misfolded proteins, damaged DNA and organelles through the inhibition of autophagy and the DNA damage response 166

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Availability of data and material Data for this review article originate from the publications in the reference list

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10.1111/nph.18437 183 WangC.YangF.ZengW.ChenX.QiuZ.WangQ.et al (2024a)

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We next assessed cytotoxic activity of dKLAK-z13 in the presence of HLAH-z13 using a cell viability assay (Fig

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