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Description
Overweight or obesity (BMI 30-plus, or 27-plus with a weight-related condition) where weight loss is the goal and there is no diabetes driving the choice

Antibodies The following antibodies and validation were used: TfR1 antibody (clone 3F3-FMA), originated from the Stockwell lab 18 , validated in this study using human DLBCL xenograft tissue

Combination therapy was defined in two ways: Ipilimumab (Yervoy) as PS with Nivolumab (Opdivo) as SS/C/I, and vice versa

GuoXZhouJStarrCMohnsEJLiYChenEPet al

It is thus of relevance to understand whether the metal core of metallothioneins can originate metal sulphide nano-crystals from the -elimination mechanism and whether these nano-crystals can play a role in the organ toxicity of accumulated metals, especially in the kidney
