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Description
Erastin and its more potent analogs imidazole ketone erastin (IKE) and piperazine erastin (PE), as well as the FDA-approved drugs sulfasalazine and sorafenib, are small molecule class 1 ferroptosis inducers

10.1161/hcg.0000000000000032 5 ChoiW.NamkungJ.HwangI.KimH.LimA.ParkH

10.1021/jf8007212 144 LuoC.SongW.ChenQ.ZhengZ.ChenK.CaoB.et al (2014)

A6: Several common medications can trigger or worsen RLS, most notably certain antidepressants (like mirtazapine and SSRIs) and some antipsychotics (like olanzapine)

ROS can modulate the activity of various transcription factors and signaling pathways involved in immune cell activation, differentiation, and function
