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Several studies have confirmed that intraarticular injection of SIN can effectively exert its pharmacological effects (138)
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Overproduction of reactive species, including hydroxyl radical (OH), superoxide anion (O 2 ), hydrogen peroxide (H 2 O 2 ), hydroperoxides (ROOH), nitric oxide (NO), and peroxynitrite (ONOO ) may lead to protein/lipid oxidation and DNA mutation
2022 August 11
doi: 10.1210/jcem-72-1-51 89 FrystykJBrickDJGerweckAVUtzALMillerKK
