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The inhibition of SIRT3 leads to the downregulation of superoxide dismutase 2 (SOD2) expression, resulting in increased levels of ROS and subsequent mitochondrial dysfunction

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Therefore, active and rapid consumption of fat stores is an ancient and conserved mechanism for surviving food deficiency 11 , which results in decreased body fat levels 7,8,9,10

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In human bodys cells, L-carnitine as an essential component has a significant role in transferring long-chain fatty acids through internal membrane of mitochondria for -oxidation process and energy production (1, 2, 6)

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