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This tolerance development explains why side effects are most prominent during treatment initiation and dose escalation but decline substantially with continued use

A Phase I Trial of Mesenchymal Stem Cells Transfected with a Plasmid Secreting Interferon Beta in Advanced Ovarian Cancer (Oral Presentation)
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HGF has been confirmed closely relating to liver repair after injury by various causes (chemical poison, infection, ischemia, physical injury or PHx, etc.)
