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[DOI] [PubMed] [Google Scholar] 100.Taha A.Y., Burnham W.M., Auvin S

The rats were dissected, and the mRNA was collected from the bladder tissue of rats

In this context, MTX fulfills several critical roles: The Baseline for Step-Up Therapy: MTX is highly effective as an initial monotherapy, but if a patient fails to achieve low disease activity or remission after a few months, clinicians typically do not replace MTX

It not only directly scavenges free radicals but also enhances the function of endogenous antioxidant defense systems by activating pathways such as Nrf2 (Nuclear factor erythroid 2-related factor 2) [185]

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