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Very long chain (C22C24) ceramides are synthesized by ceramide synthase 2 (CerS2) and a CerS2 null mouse displays hepatopathy because of depletion of C22C24 ceramides, elevation of C16-ceramide and/or elevation of sphinganine [89]

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Notably, -(1,3)-glucans are recognized by the pattern recognition receptor (PRR) Dectin-1 triggering phagocytosis of C

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