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As mismo, evaluaron los cambios de dichas toxinas antes y despus de la sesin de hemodilisis, encontrando que stas no eran removidas efectivamente por dicha terapia, elucidando as el papel de la microbiota intestinal en la formacin de solutos urmicos y su contribucin en el sndrome urmico 25

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Valproate should not be administered to a woman of childbearing potential unless other medications have failed to provide adequate symptom control or are otherwise unacceptable

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