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Tanshinone IIA alleviates NLRP3 inflammasomemediated pyroptosis in Mycobacterium tuberculosis(H37Ra) infected macrophages by inhibiting endoplasmic reticulum stress

Further research is needed to understand how cancer cells counteract its effects throughout antioxidant systems

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Considerations: Bioavailability may be lower compared to injections

The inhibition of the enzyme TRXR is proposed to be due to the stronger binding of the gold(I) to the enzymes selenocysteine, but a theoretical study found the drug could bind favorably to cysteine as well [83, 85]