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As a result, research and commercial development on the plant was prohibited for most of the 20th century ( Cannabis sativa became the most commonly cultivated black market crop in the Western world after World War II, leading to the allocation of significant law enforcement resources to remove the plants (Chouvy, 2019)

doi: 10.3390/molecules29040915

FIGURE 3 Similarly, CYP2D6 is crucial for the metabolism of paroxetine, fluoxetine, and sertraline

In A549 cells (at a concentration of 20 mol/L) and HCC827, H1650 and H1975 cells (at concentrations of 1040 mol/L), the ratio of anti-apoptotic protein Bcl-2 to pro-apoptotic proteins Bax and Bim was significantly reduced