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As there are the E3 ligases containing HECT domains, in which they continue this 'transfer chain' by accepting once again the ubiquitin via another conserved cysteine and then targeting it and transferring it to the desired target

J Anim Sci 79:31283136 Wolf LGG, Mehlman MA (1972) Subcellular distribution of pyruvate carboxylase and phosphoenolpyruvate carboxykinase in dog liver and kidney

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Thus, the findings from this review, highlighting the rich bioactive profiles of buckwheat hulls, sprouts, and extracts provide functional food developers with valuable insights into creating products that are both nutritious and aligned with health-conscious consumer preferences