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Therefore, PARP-1 activation seems to play an important role in the pathogenesis of PDN in several ways, likely including the regulation of various important inflammatory pathways

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Unfortunately, our body's production of glutathione tends to decline with age and can be influenced by lifestyle factors such as diet and exercise

oxidativer und nitrosativer Stress, zum Beispiel durch Umwelteinflsse verschiedenster Art (Insektizide, Biozide, Abgase, Elektrosmog, Schwermetalle ) nicht optimale Ernhrung (Vitaminmangel, Alkoholkonsum ) Begleiteffekte (lebens-)notwendiger medizinischer Therapien (schdliche Abbauprodukte von Medikamenten, Nebenwirkungen von Strahlentherapien oder Chemotherapien ) Auerdem entstehen freie Radikale auch als Stoffwechselprodukt bei der normalen, gesunden Zellatmung
