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doi:10.1016/S1474-4422(15)70016-5 Heo JM, Ordureau A, Paulo JA, Rinehart J, Harper JW (2015) The PINK1-PARKIN mitochondrial ubiquitylation pathway drives a program of OPTN/NDP52 recruitment and TBK1 activation to promote mitophagy
(2025) 13:e0157624
To ensure that this was indeed the case, WT, REW and PGLALA anti-NIP IgG1 variants were coated directly in ELISA wells in parallel with an IgG1 variant containing the E345R/E430G/S440Y (RGY) amino acid substitutions, which is known to form solution phase hexamers 40
It helps fight oxidative stress, supports liver detoxification, boosts immune function, and aids in cellular repair and regeneration
Therefore, it is essential to study effective therapies
