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And a plasma-activated medium (PAM) also promotes cell death by depleting FSP1 in human lung cancer cells and increasing intracellular lipid ROS [109]

[DOI] [PMC free article] [PubMed] [Google Scholar] 60

(2023) employed response surface methodology (RSM) integrated with genetic algorithmartificial neural network (GAANN) modeling, identifying optimal conditions as follows: 52 C, 1:30 solidliquid ratio (w/v), 167 min duration, and 0.01 mol/L NaOH, yielding 29.53% BSP recovery

Beginning at 300mcg allows assessment of response without overshooting the necessary dose

Lieberman P (2005): Biphasic anaphylactic reactions
