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Furthermore, citrulline participates in ammonia detoxification through the urea cycle, offering potential metabolic advantages in catabolic states with elevated nitrogen waste

In: Bloom M, Kupfer DJ (eds) Psychopharmacology: The Fourth Generation of Progress Raven Press: New York 1995

Several mechanisms control the expression and activity of MCAD, including transcriptional regulation, post-translational modifications, and substrate availability

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Nonclinical Toxicology 13.1 Carcinogenesis, Mutagenesis, and Impairment of Fertility Valproate was administered orally to rats and mice at doses of 80 and 170 mg/kg/day (less than the maximum recommended human dose on a mg/m2 basis) for two years