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Rosengren E, Rorsman H

These compounds include pyruvate, which can be converted into acetyl-CoA and enter the tricarboxylic acid (TCA) cycle or be used for fatty acid synthesis, and -ketoglutarate, a precursor of glutamate and an intermediate of the TCA cycle

Despite the large differences in weight loss between GLP-1 and GLP-1MK-801, the two compounds exhibited similar benefits on glucose tolerance in Mc4r -KO mice

Oncogene 26, 26062620
