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Consequently, while existing therapeutic strategies show promise in pre-clinical models, significant challenges such as organ specificity, potential off-target effects, and inter-individual metabolic variability must be addressed prior to clinical translation

10.1038/nm.4409 [DOI] [PubMed] [Google Scholar] 34

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10.1016/j.neurobiolaging.2011.09.021 Neurobiol

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