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Trimethylamine-N-oxide (TMAO), a molecular metabolite derived from the gut flora, has recently emerged as a candidate risk factor for many chronic diseases including cardiovascular disease, kidney disease, type 2 diabetes mellitus, and MAFLD

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[DOI] [PubMed] [Google Scholar] 6.Lewis RW, et al

Mitochondrial areas (m 2 ) were quantified in an investigator-blinded manner in 20 microscopic fields containing 2436 mitochondria (vehicle hearts) and 24 microscopic fields containing 1879 mitochondria (METH hearts) to calculate the average mitochondrial size and determine the number of mitochondria per microscopic field using NIH ImageJ (v1.6.0) software 32