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Pretreating culture medium with 120M of BSO was sufficient to inhibit glutathione synthesis after 48 hours ( Figures 5A, B )

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The androgen dehydroepiandrosterone enhances GBM resistance to temozolomide by activating the androgen receptor, thereby attenuating DNA damage
Thats why we tell patients NOT to take antioxidant supplements during cancer treatment and for at least a month afterward

Type A spermatogonia maintain the stem cell pool, whereas differentiating A spermatogonia (including intermediate forms) give rise to type B spermatogonia, which enter meiosis as primary spermatocytes